Analysis of two cDNA clones encoding the B lymphocyte antigen CD20 (B1, Bp35), a type III integral membrane protein
نویسندگان
چکیده
Two cDNA clones encoding the pan-B cell CD20 antigen were isolated from a COS cell expression library. The two clones bear identical coding sequences and differ only in the length of the 3' untranslated region. The predicted CD20 sequence is 297 residues long and contains three hydrophobic domains, one of which is long enough to span the membrane twice. COS cells transfected with either CD20 clone express an immunoreactive protein of 33 kD.
منابع مشابه
Isolation and structure of a cDNA encoding the B1 (CD20) cell-surface antigen of human B lymphocytes.
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ورودعنوان ژورنال:
- The Journal of Experimental Medicine
دوره 167 شماره
صفحات -
تاریخ انتشار 1988